COMEDI Trial
Combining a monofocal and extended depth-of-focus intraocular lens (COMEDI): an improvement in quality of vision after cataract surgery over bilateral monofocal IOL implantation?
Principal investigator: Dr. Karolien Termote
Cataract is the clouding of the crystalline lens. It can be considered a normal ageing process but can also sometimes result from an accident or inflammation. When the clouding of the crystalline lens causes visual impairment in daily activities or occupation, only cataract surgery can improve visual acuity. During cataract surgery, your own cloudy lens is removed and we insert a new intraocular lens (further called "lens") into the lens capsule. This procedure is performed under local anaesthesia with eye drops and does not require an overnight stay at the hospital.
The standard monofocal intraocular lens allows you to see clearly for one distance and requires reading glasses for reading nearby. The EDOF and multifocal intraocular lenses, on the other hand, enable you to read better from nearby as well. With EDOF intraocular lenses, however, you will still need reading glasses for the smallest letters. With multifocal intraocular lenses, you can see across all distances but visual side effects such as halos around light sources and reduced contrast in dark conditions are often observed.
Aim of the trial
For this trial, we will compare the combination of a monofocal and a EDOF intraocular lens with a standard cataract surgery where two monofocal intraocular lenses are implanted. Research shows that EDOF intraocular lenses give a better visual experience by also providing functional near vision. By having an EDOF intraocular lens implanted in one eye, we expect similar results compared to bilateral EDOF intraocular lenses. If you agree to participate in this trial, you will be randomly assigned to one of two groups: bilateral monofocal intraocular lenses or the EDOF and monofocal intraocular lens combination.